These arrived quickly and
"These arrived quickly and the packaging is informative. Unfortunately these nauseated me-some supplements do have this effect on me but my review is limited due to this. I can not adequately recommend these or not."
Complimentary Shipping on Orders $50+
Triple-Action Probiotic Blend for Mood Support
An expertly formulated 3-in-1 probiotic blend designed specifically for mood support.* Featuring clinically studied prebiotics, probiotics, and postbiotics, it provides support for cognition, mood, and occasional stress—plus digestion and immune and colon health—to help the gut and brain function at their best.* This high-quality supplement is produced in our GMP facility that is certified by NSF, with ingredients that are triple-tested to meet strict guidelines on potency, purity, and contaminants.**
Couldn't load pickup availability

Take charge of your health and emotional well-being: Give your gut and brain the support they need with this expert-formulated, triple-action probiotic formula. It’s carefully crafted with ingredients that provide powerful cognitive, mood, and occasional stress support + more.*
Prebiotic Blend: Acacia and Resistant Potato Starch, Mood Probiotic Blend, mycrobiome(R) Probiotic Blend, Postbiotic, Cellulose, Vegetable Cellulose Capsule, SIlica
Use only as directed. Take 1 Enteric VegCap daily with a meal. Do not take within two hours of taking antibiotics. KEEP REFRIGERATED.

Clinically studied prebiotics, probiotics, and a postbiotic provide potent microbiome support, delivered in our Enteric Shield® VegCaps so 28 probiotic strains arrive alive in the intestines.*

Delivers 50 billion CFU of 28 distinct probiotic strains for greater diversity including L. plantarum, B. lactis + Ls. paracasei.* CFU (colony-forming unit) is the number of live and active bacteria in each serving.
Backed by Our 60-Day Guarantee

Expert-formulated, 3-in-1 probiotic formula is carefully crafted with clinically studied ingredients to help support your gut and your brain.*
Since 1973, Solaray has believed that what you put in your body should be proven, not promised.
We source our own raw materials and triple-test every lot.
We manufacture 95% of our products for full control.
15,000 tests per month verify ingredient potency and purity.^

In an industry where quality can vary widely, testing isn't just a step in the process. It is the process.
✅ Passed Testing for Heavy Metals**
Arsenic, cadmium, lead, mercury
✅ Passed Testing for Microbials**
Mold, yeast, coliform, e. Coli
✅ Passed Testing for Contaminants**
Gluten, ethylene oxide
✅ Passed Testing for Physical Properties
Moisture, color, disintegration, tap density, mesh 140, 20, and 60
**Most contaminants, heavy metals, and microbes are tested to ensure no more than 3 ppm.

Our production facility in Ogden, Utah is a GMP facility certified by NSF. We source and triple-test raw materials, make the majority of our products in-house, conduct stringent testing in our ISO-accredited lab, and distribute our own products to ensure quality and excellence in every bottle.
Support cognition, mood, and occasional stress—plus digestion and immune and colon health*
Probiotic supplements contain beneficial bacteria that support digestive health and more.* Advanced probiotic formulas, like Solaray Mycrobiome Complete, include targeted strains for specific needs. For example, Solaray’s Women’s formula contains strains that support vaginal health; Men’s formula includes strains that support colon health.*
Yes, taking a probiotic daily can be beneficial, as consistency helps maintain a healthy balance of gut bacteria. While there are foods that support the microbiome, a probiotic supplement ensures that all of your needs are met—every day.
Probiotics help maintain a balanced microbiome by supporting good bacteria in the gut. When the good bacteria are strong, they help keep the bad bacteria in check so your body can thrive. Beyond digestion, certain advanced probiotics include strains that support immune health, mood, cardiovascular health, and more.*
Each probiotic strain has unique properties and targets specific aspects of health. The combined effect of multiple strains may be greater than the effect of individual strains alone.
Solaray experts selected strains that address the needs of different groups of people. For example, our Women’s formula features strains that support vaginal health and occasional stress, while our Active formula includes strains that provide exercise and respiratory support.*
The microbiome is the collection of all the microbes, including bacteria, viruses, and fungi, that naturally live in your body. In relation to probiotics, the term usually refers to the gut microbiome: the microorganisms found in your gastrointestinal tract. The gut microbiome and brain function are connected via the gut-brain axis, with microbiome health linked to cognitive function and mood regulation.
Studies linking probiotics and mood support have been conducted on a range of strains and blends, indicating that more than one type of probiotic may offer the support you need. In general, multi-strain probiotics are considered more effective than single-strain options. Formulations that also include prebiotics, which act as nutrition for gut bacteria, can further help the microorganisms in probiotics flourish. Our Mood formula includes 28 diverse, clinically studied probiotic strains that were expertly selected to support cognition, mood, and occasional stress.* It delivers 50 billion CFU (colony-forming unit), the number of live and active bacteria in each serving, plus prebiotics and a postbiotic.
A growing body of research connects improved mood outcomes with the use of probiotics due to the relationship between gut health and brain function. In a review of nine clinical trials that saw participants treated with probiotics or prebiotics, eight resulted in significantly improved mood.
Probiotics are generally considered safe for healthy individuals, but may not be suitable for people with immune system concerns or severe illnesses. In addition, probiotics can interact with some prescription medications. Do not take probiotics within two hours of taking an antibiotic, as antibiotics can reduce probiotics’ efficacy by killing many of the live microorganisms they contain. You should also avoid mixing them with antifungals or immunosuppressants. If you’re unsure whether a probiotic is right for you, consult your healthcare provider.
For additional mood support, consider Solaray StressMag and Solaray SharpMind Nootropics Mood. StressMag combines our in-house chelated magnesium glycinate with a clinically studied form of ashwagandha, which provides powerful support for relaxation, mood, and occasional stress while helping regulate the body’s stress response system.* SharpMind contains 25 mg of clinically backed Zembrin®, observed to deliver an alert serenity to support mood, focus, and an overall sense of well-being*†, plus 200 mg of the adaptogen Holy Basil, 5 mg of Lithium, and 200 mg of fermented organic, US-grown Reishi mushroom for additional support.
Disclaimer: The customer reviews and testimonials featured on this site reflect individual experiences and opinions. Results may vary and are not guaranteed. These statements have not been evaluated by the Food and Drug Administration (FDA). The content is not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare professional before starting any new supplement regimen or if you have concerns about your health.
Overall rating: 4.257143 / 5 from 35 reviews.
Mycrobiome Complete Probiotic Mood offers a triple-action formula with potent support for cognition, mood, and occasional stress. Customers appreciate its small, easy-to-swallow capsules, clean ingredients, and the fact that it provides good gut health. The product also offers great value for money and is easy to take with food.
Review topics: ["ingredients","improvement","feel","difference","benefits","value","texture","probiotic","packaging","effects","stomach","capsules","aftertaste","supplement","support","mood","health","stress","strains","digestion"].
"These arrived quickly and the packaging is informative. Unfortunately these nauseated me-some supplements do have this effect on me but my review is limited due to this. I can not adequately recommend these or not."
— Aowens1311 4. (3/5)
"The packaging is super easy to work with! The taste and texture of the capsules are smooth going down. No complaints from me! I really love all the familiar ingredients listed. Can't wait for the amazing results!"
— Skyeb15 5. (3/5)
"Have been taking them kinda off and on when I can remember to take them. They seem to help with gut health and mood which is good. I would recommend to anyone who is looking for a probiotic."
— Courtneyann7 3. (4/5)
"I've been taking the Solaray Microbiome Complete Mood: Pre-Pro-Postbiotic for a few weeks and I'm really happy with the results. The effectiveness is noticeable ' I feel less bloated and my digestion has improved, plus I've experienced a subtle lift in my overall mood. The taste is neutral and easy to take, which I really appreciate compared to other probiotics. I like the clean ingredients list without unnecessary fillers, which makes it feel like a high-quality supplement. The packaging is sturdy, informative, and easy to store. For the value, I think it's fair considering the combination of pre-, pro-, and postbiotics in one product."
— Elenak104 1. (5/5)
"Taking probiotics especially when you are older is a must for well being and to have the immune health. Solaray Mood is one that I take over three weeks and I feel great with my stomach, not having nausea or stomach issues, just great feeling that support works like supposed to. Capsules are tasteless and have slight scent, suggested to keep it in the fridge, so far I am pleased and continue to use, suggest to others."
— Irinah 1. (5/5)
"I think this product may make a difference but I hate having to review a supplement after less than a month of use because it is almost impossible to tell whether it works in such a short time. I do have stomach issues that seem to be slightly better since starting this, but I don’t notice the “mood support”. It may be that it takes more time, like most supplements, but because of the review requirement, I don’t know."
— Jenp123 9. (3/5)
"I've been using these products for a while, and I can genuinely feel a significant improvement in my mood. The effects are quite noticeable and uplifting. One of the best aspects is that there’s no unpleasant aftertaste, which can often be a drawback with other supplements. Additionally, I'm pleased to see that all the ingredients are entirely natural, giving me confidence in what I'm putting into my body. This combination of effectiveness and quality is truly commendable."
— Darsheimaa1 1. (5/5)
"Love that these capsules are small and easy to swallow. They have no real taste although I don't keep them in my mouth for long before swallowing with water. I like that they have pre. Pro, and post biotics for overall gut health. For me personally, probiotics do help my body with digestion. As far as being a mood booster, I'm not sure these have effected me or not but it's an added benefit that could help everyone 😉"
— Mandys77 2. (4/5)
"SOLARAY Mycrobiome complete is my new favorite product! This is Formulated for Women, helps with Digestion, Mood & Urinary Tract Support! It really does do what is says. I feel so much better since taking this. It’s helped my immune system to fight off viruses along with giving me a feeling of overall wellbeing. I suffered with gut issues for years. My IBS problems stopped shortly after I started taking it! ! This has so many strains of prebiotics and probiotics! More than any other formula I’ve ever tried. It helps to build up your gut to make your body stronger and more resilient to stress and gastrointestinal problems. I would absolutely recommend it to everyone!"
— Klreb 9. (5/5)
"The softgels are easy to swallow, and it doesn’t irritate my stomach. It comes in a 30 day supply, two gels a day. Ingredients appear to be of a good quality. I wouldn’t be able to say if it works but I feel good about taking this supplement. It doesn’t have any taste to it."
— Solpal 4. (5/5)
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.